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The phytochemical study of flowers and green fruits of Senna spectabilis furnished a new substituted 2,6-dialkylpiperidin-3-ol alkaloid, named (-)-7-hydroxycassine, along with five known piperidine alkaloids: (-)-cassine, (-)-spectaline, (-)-3-O-acetylspectaline, (-)-7-hydroxyspectaline and (-)-iso-6-spectaline. In addition to non-alkaloidal, chemical constituents from other chemical classes were also identified, including the steroid β-sitosterol, the flavonoids luteolin and 3-methoxyluteolin, the triterpene betulinic acid and trans-cinnamic acid. To our knowledge, compounds are being reported for the first time in this species. © 2013 Sociedade Brasileira de Quimica

journal of the brazilian chemical society

(–)-7-Hydroxycassine: a New 2,6-Dialkylpiperidin-3-ol Alkaloid and other Constituents Isolated from Flowers and Fruits of<i>Senna spectabilis</i>(Fabaceae)

(–)-7-Hydroxycassine: a New 2,6-Dialkylpiperidin-3-ol Alkaloid and other Constituents Isolated from Flowers and Fruits ofSenna spectabilis(Fabaceae)