English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

photosensitized mutation of Escherichia coli, it was found that riboflavin actually had photodynamic activities which were extremely enhanced by the presence of adenine. The riboflavin-adenine system revealed its photodynamic activities on various biological systems including Staphylococcus aureus, bacteriophages, Influenza virus, and Shigella flexneri antiserum. The concentration of ribo flavin and adenine usually used were 20 and 200ƒÊg/ml, respectively. The effec tive wave length of light for the photo dynamic activities of riboflavin-adenine system coresponded to that of the light absorbed by an aqueous solution of ribo flavin. The presence of molecular oxygen was essential for the activities, any residues of which, however, were not recognized after turning off the light. Among the related compounds tested, lumiflavin and flavin mononucleotide were as active as riboflavin. Adenine was replaced by hypoxanthine and to lesser extent by thymine and uracil. Chelating agents such as ethylenedia mine tetraacetic acid and S-hydroxyqino line deprived the system of the photo dynamic activities. Detailed data will be presented else where by K. Nigota. Comparative studies of the inactiva tion of bacteriophages T1 and T2 pro vide a clue to the mechanism of the photodynamic inactivation by the ribo flavin-adenine system. It has been sug gested that the T-even phages have barriers preventing the rapid diffusion of the dye (toluidine blue, methylene blue, proflavin, etc.) molecules, while the T-odd phages must have a more per meable head structure, and that the phage DNA is a major target for photo dynamic inactivation (Yamamoto, 1958; Helprin and Hiatt, 1959; Ritchie, 1965). In our experiment with riboflavin and adenine, however, phage T2 as well as

The Photodynamic Action of Riboflavin-Adenine System on Bacteria, Bacteriophages, Influenza Virus, and Shigella exneri Antiserum