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Obesity as a chronic disease causes many diseases. Vaspin is a new adipokine, which increase as a result of inflammation resulting from obesity and metabolic diseases (3). Regular exercise has a variety of benefits, including increasing insulin sensitivity, controlling blood sugar (glucose), losing weight, decreasing body fat percentage, reducing inflammation stress. Kadoglou et al. (2013) reported that six months aerobic exercise with 65 to 75 per cent of maximum heart rate causes increasing serum vaspin level in type II diabetes patients. While Eberbach et al. (2010) reported decreasing serum vaspin after intense training. Different factors and mechanisms involve in the development of cardiovascular diseases, the most important factors are changes in inflammatory factors and lipids disorder including poor concentration of HDL, LDL, TG, and TC (4). The aim of this study is to investigate the effects of 8 weeks rhythmic aerobic exercise on vaspin and lipid profile in overweight and obese women. After calling among women, 34 people of overweight and obese women (40 ± 10 years, BMI ≥ 25) in Zahedan on a voluntary basis and available and based on inclusion and exclusion criteria were selected. Then, the subjects were randomly divided into two groups of training (n = 17) and control (n = 17). The training group commenced training in an 8-week training program, three sessions per week (each session 60 minutes), with 55 per cent of maximum heart rate during the first week, and gradually, with the development of training programs reached 85 per cent of maximum heart rate. Each workout included the aerobic movements of low impact and high impact in a standing posture and returning to the primary state in a sitting posture. While, were asked the control group to maintain their normal lifestyle during the study. Blood samples in two stages were taken: first, 48 hours before the test and then, 48 hours after the last meeting of rhythmic aerobic exercise. Serum vaspin concentration and lipid profiles were determined by ELISA method using a special kit. To recognize similarity and normality of the data related to the subjects of the research groups was used Shapiro-Wilk test. To analyze the data was used the paired T test and the covariance test to show differences within group and between groups at the level of 5%. Statistical calculations were done by SPSS 21. Data analysis showed that 8-week exercise had a significant effect on BMI (P = 0.001), weight (P = 0.000), vaspin (P = 0.003), HDL (P = 0.000), LDL (P = 0.001), and TC (P = 0.001), while had no significant effect on TG (P = 0.692). Exercise intervention with respect to the basis levels of vaspin may show different effects. In other words, the health of the subjects, overweight and lack of physical activity can be one of influences in response to this variable to physical activity. Hence, it seems that in this study, a significant decrease in BMI of the experimental group than in the control group and most likely, reducing inflammatory levels has led to the adjusted response in vaspin levels. Furthermore, aerobic exercise can be considered as the effective method for changing in the lipid profile. It seems that physical activities also cause increasing lipolysis and reducing fatty acids in the blood and muscles. DOI: 10.5901/mjss.2016.v7n4S2p163

The Effect of 8 Weeks Rhythmic Aerobic Exercise on Vaspin Levels and Lipid Profile in Overweight and Obese Women