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Objective: To determine relationship between blood lactatelevel and mortality rate in children admitted to theintensive care unit.Methods: 298 critically ill patients aged between 28 daysand 16 years admitted to Dicle University Hospital, thethird step Pediatric Intensive Care Unit in between January2007 and December 2007 were included. Age, sex,diagnosis, Glasgow coma score points, the first measuredblood lactate levels (lactate 1) and the arithmeticaverage of all measured blood lactate levels during treatment(lactate 2) of cases were evaluated. Patients weredivided into group A (lactate < 20 mg/dl) and B (lactate ≥20 mg/dl). According to the results, patients were classifiedas survivors and non-survivors. Both lactate 1 andlactate 2 were compared with mortality rates.Results: In this study, a total of 298 patients were evaluated,158 of them were nonsurvivors and 140 were survivors.A significant correlation was found between lactatelevels and mortality rates. Lactate levels were higher innon-survivor cases (p<0.001). In group B, lactate 1 had68% (106/156) sensitivity and 75% (106/142) specificityfor determining the risk of mortality. Also in group B, lactate2 had 85% (134/158) sensitivity and 79% (134/169)specificity for determining the risk of mortality.Conclusion: There is a strong association between highblood lactate levels and mortality rates in the critically illpatients in pediatric intensive care unit. In these patientsblood lactate levels can be used for follow-up and evaluationof the effectiveness of treatment and determiningmortality. J Clin Exp Invest 2013; 4 (3): 269-273Key words: Pediatric intensive care unit, critically ill children,blood lactate levels, mortalit

The relationship between blood lactate levels and mortality in pediatric intensive care patients