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Central Mucoepidermoid carcinoma (cMEC) is uncommon entity and occurs commonly in the mandible, but rarely in the maxilla. Furthermore, the occurrence of cMEC in children and adolescents is extremely rare. An 18-year-old male patient was referred to our hospital because of halitosis and fistula of the palate. Radiological examination showed a cystic lesion in the right side of the maxilla with bone destruction. The histopathological diagnosis on biopsy was MEC. Partial maxillectomy was successfully performed. There has been no evidence of recurrence or metastasis as of 3 years after the operation. Real-time RT-PCR assay of paraffin-embedded tissue showed positivity of MEC-specific CRTC1-MAML2 gene fusions, suggesting a good prognosis.

A case of central mucoepidermoid carcinoma of the maxilla in an 18-year-old male patient