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Marfan's syndrome (MFS) is a dominantly inherited connective tissue disorder caused by mutations in the FBNl gene. The disease affects mainly the skeletal, cardiovascular, and ocular systems. In the oral region, MFS is often associated with a high-arched and narrow palate, with crowding and impaction of the teeth. The condition of the periodontal membrane is an important determinant of the successful autotransplantation of teeth. We believe that this is the first report to document the autotransplantation of teeth in a patient with MFS. A 14year-old boy was referred to the Department of Oral and Maxillofacial Surgery, Tokyo Medical and Dental University because of malocculusion. Intraoral and X-ray examinations revealed crowding of the teeth, supernumerary teeth, and impaction of the inverted upper central incisor. After consultation with orthodontists and pedodontists, he underwent extraction of the supernumerary teeth and concurrent transplantation of the impacted upper right central incisor to the original position. Before transplantation, the incisor was apicotomized because of severe root tip curvature. The postoperative course was uneventful. The upper central incisor underwent root canal filling 3 weeks after transplantation, and orthodontic treatment, including the transplanted incisor was successfully started 3 months after transplantation. The transplanted incisor is surviving with no evidence of abnormal root resorption and is functioning well.

Autotransplantation and orthodontic treatment of a maxillary anterior tooth in Marfan's syndrome: a case report