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We report a case of extranodal NK/T cell lymphoma, nasal type, which is a non-Hodgkin's lymphoma according to the new World Health Organization classification. A 69-year-old man was referred to our hospital because of a necrotizing ulcer on the right side of the maxillary gingiva. Computed tomography showed a soft tissue mass in the both paranasal sinuses, but no evidence of bone destruction. Histologic features included various inflammatory cells in the bottom of the ulcer. High fever, night sweat, and loss of body weight were noteds and the ulcer extended to both sides of the maxillary gingiva and palate. Ga and Tc scintillation scanning showed marked accumulation in the maxilla. Immunoohenotypic analysis of a biopsy specimen revealed that CD56 and Epstein-Barr virus encoded small RNA in situ hybridization (EBER ISH) were positive. The patient was given a diagnosis of extranodal NK/T cell lymphoma, nasal type, stage I E. The patient received chemotherapy with CHOP and radiotherapy. However, these therapies were not effective, and the patient died of lung metastasis.

A case of extranodal NK/T cell lymphoma, nasal type arising bilaterally in a necrotizing ulcer of the maxilla.