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The purpose of this study was to investigate the time of change in the reaction between mandibular bone tissue and glass ceramic implants under functional loads.Two months after extraction of P2, P3, P4, and Ml, from the mandibles of 16 adult mongrel dogs, glass ceramic implants were implanted in each side, and the glass ceramic implants were under a functional load three months after implantation. Histological examination and tetracycline labelling of the specimens were made 10 to 300 days after initiation of the function. The results obtained were as follows:At 10 to 30 days after initiation of the function, new bone formation was found around the glass ceramic implant, the new bone increased in thickness and ankylosed, showing a network structure. After 60 to 90 days, there was new bone formation and bone remodeling, after 120 to 150 days, there was a supporting growth of spongy bone tissue, and the new bone was mature. After 300 days, the functional load was around the implant and the mandible bone.The tetracycline labelling method showed strong labelling after 10 to 30 days continuing up to 60 days and then decreasing gradually until 90 days.The results of this experiment confirmed that glass ceramics has high tissue affinity for mandibular tissue and the placement of the glass ceramic implants under functional loads caused no problems around the implant. We established that it is an appropriate material for implants.

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An experimental study on histological changes in the mandibular tissue of CaO-P2O5-MgO-SiO2-CaF system glass ceramic dental implants under functional loads.