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Cleft lip and palate is the most common abnomalities among congenital facial malformation. However, it is very rare that both twins have cleft lip and palate. Zygosity diagnosis is very important for the investigation of the etiology of this malformation. In twins with cleft lip and palate reported here, zygosity diagnosis was done by the similarity method, blood type and HLA halotype. From these results, we concluded that they were monozygotic.

A case of monozygotic twins with cleft lip and palate.