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Potassium bromate intoxication shows acute renal failure, hearing loss and neuropathy. We report a 56-year-old woman who drank a solution of cold wave neutralizer ina suicide attempt. The patient showed severe renal failure, neuropathy and sensory neural hearing loss, but there was no vertigo r vestibular disorder. Early continuous hemodiafiltration(CHOP)after potassium bromate ingestion was effective for these symptoms. Slight improvement of renal failure and hearing loss, and complete improvement of neuropathy were confirmed on long-term evaluation. At present, dialysis is not required, and the patient can converse smoothly using a hearing aid. We investigated 81 cases of bromate intoxication i cluding the present case, reported in Japan up to 2006.Renal failure occurred in all cases, hearing loss and neuropathy were described in 56/65(86%) and 21/21(100%),respectively. These symptoms should be caused by the direct oxic effect of bromate. The cause of hearing loss seems to be disorder of the stria vascularis. We hope that a new cold wave neutralizer that does not contain o potassium bromate will become more widely promoted by the cosmetic industry.

A Case of Hearing Loss Due to Potassium Bromate