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The paper presents an analysis of cases of treatment of humeral shaft fracture non-union following operative treatment. Non-union was treated by locked intramedullary nailing in all patients. Bone destruction at the fracture site is an indication for using bone grafts. In our opinion autologous bone marrow injection to the fracture site is an effective method of bone union stimulation, and this non-invasive procedure may be repeated several times. Stable osteosynthesis promotes callus formation and remodeling, and enables early rehabilitation.

Locked intramedullary nailing in the treatment of non-union following humeral shaft fractures