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The impact of SpO2 target ranges (TR) has been carefully studied; however, reports suggest a wide variation among infants and centres in maintaining the intended range. Little is known about the effectiveness of different approaches to manual control. Auto-SpO2 controllers are now available which show promise.

Quicker response results in better SpO2 control – a comparison of 3 FiO2-titration strategies in ventilated preterm infants