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Most orbital tumors of infants include retinoblastoma, dermoid cyst (teratoma), optic nerve glioma and nevus, and hemangioendothelioma is found in rare cases. Hemangioendothelioma, the tumor of intermediate malignancy between angiosarcoma and hemangioma, is commonly recognized in soft tissue of extremities, skin, lung and liver with symptoms of ulceration and hepatomegaly in neonates and infants. However it seldom localizes in the orbit. Although there have been two case reports of orbital hemangioendothelioma in neonate and adult in Korea, there was no case report of prenatally diagnosed orbital hemangioendothelioma in fetus. We found hemangioma-like orbital tumor in a fetus at 36 weeks of gestation by prenatal ultrasonography and confirmed hemangioendothelioma by microscopic examination after birth. This is the first case of orbital hemangioendothelioma in fetus.

An orbital hemangioendothelioma of fetus detected by prenatal ultrasonography