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ularly among postmenopausal women. However, it is rarely associated with pregnancy. Pregnancy and lactation-associated osteoporosis (PLO) usually occurs in the last trimester of pregnancy or in the early postpartum period. The prevalence of the disease is estimated to be 48 for every million patients.1 The etiology of the disease remains unclear, but genetic, environmental and hormonal mechanisms are claimed to be the possible causes.2 The leading symptoms include bone marrow edema and acute back pain depending on vertebral fractures.

Pregnancy and Lactation-Associated Osteoporosis with Vertebral Compression Fractures: Two Case Reports