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Objective: To evaluate and compare the levels of plasma total cholesterol, low density lipoprotein, very low density lipoprotein, high density lipoprotein and triglycerides among the oral sub mucous fibrosis patients and control group. Design of the Study: It’s a comparative study done with simple random sampling. Study Settings: The study was done at Oral pathology department of Fatima Jinnah Dental College and Hospital from 01-04-2017 to 30-09-2017. Material and Methods: This research was conducted on 30 clinically diagnosed cases of OSMF and 30 healthy controls. The total lipid profile including triglycerides, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol and very low density lipoprotein cholesterol was evaluated. Results of the Study: CTSS The serum lipid values were decreased considerably in the cases than in the controls. Conclusion: There is a converse affiliation between lipid profile and occurrence of oral submucous fibrosis. Consequently the reduced lipid values may be used as a valuable tool in the premature detection of oral submucous fibrosis. Keywords: Oral squamous cell carcinoma, lipids, premalignant condition

Evaluation of Serum Lipid Profile in Patients Suffering from Oral Submucous Fibrosis