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Reading centres are a concept to enhance the results and the acceptance of clinical trials. Computerised systems provide the possibility to improve reading centres in a significant way. However ophthalmic reading centres often do not fully use the potential of computerised systems. In this paper we show some of the advantages sophisticated software can provide over traditional methods like e-mail. The improvements can be structured in the following categories: Decreasing the chance of human mistakes; optimizing data exchange and data flow; enforcing SOPs and complex workflows; further improvements. Large parts of the proposed methods were successfully implemented in a proof of concept system for the Tuebingen ERG Reading Centre that can serve as a reading centre in large ophthalmologic multi-centre clinical trials.

QUALITY IMPROVEMENTS FOR READING CENTRES - Methods to Improve Quality and Compliance using Computerised Systems