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An endoscope apparatus includes a solid-state image pickup device, a memory, a display, and an illumination system. The solid-state image pickup device is mounted at the distal end of an insertion portion to be inserted in a body cavity and picks up an image of the body cavity. The image pickup device forms a one-frame image by a plurality of fields. The memory stores the one-frame image formed from an image signal of succeeding fields obtained from the image pickup device. The display displays the image stored in the memory. The illumination system illuminates an object portion for the image pickup device with at least one light pulse in units of fields. The illumination system sets radiation phases of the light pulses in the first and last ones of the major fields constituting the one-frame image to be close to each other.

HOW MUCH SEQUENCE IDENTITY GUARANTEE GOOD MODELS IN HOMOLOGY MODELING - Proteins from Serine Protease Family as a Test Case?