English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

. ZNF33B belongs to recently duplicated Krüppel-associated box domain zinc finger proteins (KRAB-ZFPs), whichis widely present in various organs, and some evidence showed that itsexpression is altered in the ovary undergoing superovulation. In this study,the expression of ZNF33B in ovary and early embryo was determined byimmunohistochemistry and immunofluorescence techniques. Results showed thatthe expression of ZNF33B in the ovary was mainly in the cytoplasm of oocytesand granulosa luteal cells of ovarian corpus luteum and significantlyreduced during follicular ovulation to luteal degeneration. The expressionof ZNF33B in the early embryo transferred from the nucleus to the wholecell, suggesting that the expression of ZNF33B is spatiotemporally specific.Then, in combination with the single nucleotide polymorphism (SNP) database, the g.-61G&gt;T mutantof the 5′-untranslated region (5′ UTR) of the ZNF33B gene was screened out from 556Changbaishan black cattle, and the frequency of the mutant gene was counted.The statistics of superovulation and superovulation traits confirmedsignificant differences between the two genotypes in the quantity andquality of oocytes obtained after superovulation. This study confirmed, forthe first time, the effect of ZNF33B gene polymorphism on superovulationtraits and suggested that the mutation could provide a basis for cattlebreeding and improving animal fertility.

Expression pattern of ZNF33B in bovine ovaries and the effect of its polymorphism on superovulation traits