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The aim of this study was to investigate, if special genotypes of the genes glutathione peroxidase 5 (GPX5),fucosyltransferase 1 (FUT1) and estrogen receptor 2 (ESR2) are associated with litter size in a commercial pigcross population. For this purpose, a total of 123 F<sub>2</sub> sows were divided into two extreme performance groups,one with a high litter size (n = 61, ≥ 14.3 piglets per litter) and one with a low litter size (n = 62, ≤ 11.3 pigletsper litter) and genotyped using PCR-RFLP methods. The Chi-square test was used in order to investigate, if aspecial genotype occurs significantly more often in one of the two performance groups (p < 0.05). Whereas noassociation was found between different ESR2 or GPX5 genotypes with one of the two performance groups, thenumber of sows with AB genotypes at the FUT1 gene was significantly increased in the high performance groupin comparison to the low performance group

Analysis of association of GPX5, FUT1 and ESR2 genotypes with litter size in a commercial pig cross population