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The use of plants in the treatment of various diseases is widespread throughout the world. In the world, especially in poorer regions the use of cheaper treatments is of paramount importance. The wound care remains a major medical important issue, particularly in surgical practice, at a time when the indiscriminate use of antibiotics has hampered hospital treatment of patients, with repercussions on the increasing emergence of antimicrobial-resistant microorganisms. Adjuvants are substances that have various functions before the drugs which they are presented. Have functions as increasing solubility, suspend, increase viscosity, dilute, lubricate, stabilize, promote flow, coalesce, disintegrate, save and modify the release of drugs, one of the builders who has been used in pharmaceutical research is the SBA-15, since the same physical-chemical properties with great potential as mucosal adjuvant. This study aims to test the SBA-15 as adjuvants, preserving the effects of the drugs in which are likely to be tested. The sample of SBA-15 was synthesized in an acid medium by hydrothermal method Using the P123 as organic driver and TEOS as a source of silica. The sample obtained was characterized by XRD techniques, TG / DTG and DSC.O SBA-15 was added to mechanically ointment until it reached a certain homogeneity. The mesoporous materials SBA-15 was successfully synthesized according to literature to be mixed with the same ointment acquired a good texture. A test was performed where the pure ointment was placed and the SBA-15 at a temperature 5 degrees C ° and observed visually the change of texture. The ointment with SBA-15 was more resistant.

Síntese, caracterização e utilização da peneira molecular SBA-15 como adjuvante em fármaco.