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With the broadening of its diagnostic criteria of recent years, cases of MFH (malignant fibrous histiocytoma) have been on the increase, and its clinical feature also has come to greatly diversify. Nothing truly convincing has, however, been reported as regard the therapy effective against this particular disease.Eight cases have so far been diagnosed as MFH by this Department since 1978, and the patients so diagnosed were aged from 19to 72, or 44 years old on the average.Of the eight cases, three were located at the proximal portion of thigh, two at the distal portion of thigh, one near the knee, one at the proximal portion of upper arm, and one at the retroperitoneum, of which two were regarded as being of bone origin.For the purpose of reducing the local focus activity as well as of preventing the recurrence of the disease, the radiation therapy with about 4000 to 6000 Rad. has been administered on the patients by this Department before and after the surgery.Comparative studies made, principally, of observations which were obtained before and after the radiation therapy performed on the patients show that this radiation method of treatment can be expected to offer a considerable local effectiveness in some particular instances.

Experience of the radiation therapy for malignant fibrous histiocytoma.