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Source of support: Nil Conflict of interest: None daneous permanent teeth. Hence, the preservation of primary tooth structure is necessary, provided that it can be restored to function and remain free from disease.1 The pulpectomy treatment in necrotic and abscessed primary teeth shows acceptable results in approximately 85% of the cases, but it presents various challenges because of the continuous changes in the apical foramen as a result of physiologic and pathologic root resorption.2 Endodontic management of necrotic and abscessed primary molars is generally complicated and is more challenging and difficult in uncooperative children due to behavior management problems, restricted mouth opening, root canal system complexities, a risk of damaging the permanent tooth bud and require multiple visits.3 Hence keeping in view the need, the Cardiology Research Unit of the Niigata University School of Dentistry developed the concept of LSTR therapy or non-instrumentation endodontic treatment (NIET) which employs the use of triple antibiotic paste for disinfection of oral infectious lesions, which includes dentinal, pulpal, and periapical lesions.4 The present study aimed to clinically evaluate LSTR therapy with triple antibiotic paste which includes a mixture of ciprofloxacin, metronidazole, and minocycline (3 Mix-Paste) in endodontic treatment of infected primary teeth, including those with physiologic root resorption.

Lesion Sterilization and Tissue Repair—A Recent Novel Approach for the Treatment of Very Uncooperative Pediatric Patients