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Ab s t r Ac t Aim and objective: The main aim of reporting this case is to make the clinician aware of a rare collision tumor of the thyroid gland and a systematic approach to such cases. Background: Collision tumors, though reported frequently in other organs, are an uncommon pathology in the thyroid gland and present as a diagnostic and treatment challenge. Case description: This is a case of follicular and papillary carcinomas occurring simultaneously in different lobes of the thyroid gland as a collision tumor. This is an extremely rare entity, with only three cases found to be reported on a detailed search through the literature. Clinical significance: Management of such dual pathology tumors is complex and should be patient-specific and directed toward more aggressive tumors; however, such clinical scenario lacks standardized diagnosis and management protocol due to lack of comprehensive knowledge regarding the behavior of such collision tumors. This case report is therefore an attempt to guide the clinician in the management of such cases.

An Approach to a Rare Case of Collision Tumor of Follicular and Papillary Carcinomas of the Thyroid