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The use of medicinal plants in traditional medicine is well known in rural areas of many developing countries (Gupta et al., 2005; Sandhu & Heinrich, 2005). According to World Health Organisation (WHO) more than 80% of the World’s Population rely on traditional medicine for their primary health care needs (Ammara et al., 2009). Human have always relied on plants for shelter, clothing, equipment, dental care, medicine, drinks and to nourish and sustain the body (Oladunmoye et al., 2009). Medicines obtained from plants are relatively safer than synthetic alternative (Iwu et al., 1999; Idu et al., 2007).

Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of <i>Boerhavia diffusa</i> L.