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Antibacterial activity of Garcinia kola (Bitter Kola) and Cola nitida (Kola nut) against Staphylococcus aureus, Salmonella typhi, Escherichia coli and Klebsiella pneumoniae was studied. Results showed that alcohol extract of Garcinia kola was active against Staphylococcus aureus and Klebsiella pneumoniae at various concentrations, with the latter displaying the lowest sensitivity. Escherichia coli and Salmonella typhi were completely resistant. Hot water extract of the same plant was however, active against Salmonella typhi, Staphylococcus aureus and Klebsiella pneumoniae . The other organisms showed sensitivity to the alcohol extract of Cola nitida , but higher sensitivity was observed with the hot water extract of the plant. Some of the results provided scientific evidence for the use of the plants by traditional herbalists in the treatment of microbial infections. Key word: Garcinia kola, Bitter Kola, Cola nitida, Kola nut, Antibacterial, extracts.

Antibacterial Activity of <i>Garcinia kola</i> and <i>Cola nitida</i> Seed Extracts