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Two hundred and twenty two (222) students in Junior and Senior SecondarySchools were sampled in the Agona District in the Central Region of Ghana to find out the extent of their sexual activity and their awareness on HIV/AIDS. The results show that the students were sexually active and some of them started at the early stage of 8 years. The boys were more sexually active than the girls. However, a large number of those of them engaged in sex (76.66%) did not use the condom. Though 63.05% of respondents knew that HIV/AIDS is caused by a virus (a germ) some others believe that HIV/AIDS is as a result of curse or punishment from God or gods and only offenders contract the disease. Despitethe fact that most of the respondents had good knowledge of the modes of spread, symptoms, preventive measures and ways of living with people living with HIV/AIDS (PLWHA) a large number of them also had different kinds of misconceptions. The differences between the total frequencies were very highly significant (X2 = 44.77, P African Journal of Educational Studies in Mathematics and Sciences Vol. 4 2006: pp. 61-75

Students' Knowledge about Sex and HIV/AIDS: The Case of Agona District in the Central Region of Ghana