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Until recently, children requiring long-term parenteral nutrition who experienced parenteral nutrition‐associated liver disease (PNALD) were likely to die from infection or liver disease before receiv ing a small bowel and/or liver transplant. 4 With the introduc tion of parenteral fish oil (10% long-chain omega-3 fatty acid emulsion; Omegaven, Fresenius Kabi, Bad Homburg, Germany), originally indicated for use in combination with a soybean oil‐based lipid emulsion (Intralipid), we have been able to reverse this life-threatening condition in several infants without the need for transplantation. We present our experience with parenteral administration of fish oil in 8 infants with PNALD. Verbal informed consent for publication was obtained from the patients’ guardians. No ethics approval was required by our institution.

Use of Parenteral Fish Oil to Reverse Cholestasis Induced by Parenteral Nutrition in Infants with Intestinal Failure: Single-Centre Case Series