English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In this review the Authors will explain the pathophysiological mechanism of action of the oxygen ozone therapy in the treatment of the disc herniation and knee arthritis. The ozone injected in the intervertebral disc or in the joint causes a rapid oxidative reaction with the organic compound of disc and synovial fluid and a late response due the formation of various second messengers that are able to stimulate the endogenous production of antioxidants through a hormetic production of hydrogen peroxide. As a consequence of the intradiscal or intrarticular injection of ozone we noted a dramatic decrease of the pain and a reduction of the local and systemic inflammation. The ozone therapy is cost-effective and should be used to improve recovery of the disc herniation and knee arthritis.

Disc Herniation and Knee Arthritis as Chronic Oxidative Stress Diseases: The Therapeutic Role of Oxygen Ozone Therapy