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Background: Global burden of HIV/AIDS remain enormous. Ethiopia is one of the Sub-Saharan countries that are hardly hit by the HIV/AIDS epidemic. Adherence is a vital component and main concern knotted with strategic decisions in service provisions. Therefore, the main objective of this study was to assess adherence to antiretroviral treatment and associated factors among clients attending ART clinics in Hosanna town. Methods: Cross sectional study design using both quantitative and qualitative methods of data collection was conducted from January to February, 2015. Consecutive sampling technique was applied to select individual client. Data was analyzed by using SPSS version 16.0. Binary logistic regressions were used to identify independent predictors. Qualitative data was collected using in-depth interview with clients and health providers and used for concurrent triangulation with quantitative one. Results: The study revealed that adherence rate to ART treatment of clients was 90.70%. As independent predictors, rural residents [AOR (95%CI)=2.14 (1.12 to 3.01)], and marital status (divorced) [AOR (95%CI)=2.37 (1.33 to 4.24)] were positively associated with non-adherence whereas living alone [AOR (95%CI)=0.37 (0.19 to 0.72)] and perceived availability of services [AOR (95%CI)=0.16 (1.03 to 1.31)] were negatively associated with non-adherence. In total, 76.98% of the variance in the quality of services in terms of adherence could be explained by Donabedian model. Conclusion: Despite higher numbers of clients was adherence to ART treatment, considerably intolerable numbers were below level of adherence in the service provided. Therefore, due attention should give to fill the gap of perception of the clients to existing services through ART mentorship by inaugurating with IEC/BCC in the context of their residence, educational level and living conditions.

Adherence to Antiretroviral Treatment Services and Associated Factors among Clients Attending ART Clinics in Hosanna Town, Southern Ethiopia