English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: Phytogenic compounds are one of many alternatives to current  industry feed ingredients for the poultry industry. However, despite increased  reports on the activity of phytogenic compounds against disease in poultry,  there is a lack of data regarding safety and residual toxicity. This two-part study  investigated the general health of broiler chickens fed Berberine, Ursolic Acid,  Piceid, Honokiol and Baicalin in-feed at three different levels, and assessed the  poultry tissue residue of Berberine in breast muscle, upper and lower thigh, and  liver through LC/MS-MS. Methods and Findings: Phase 1 trial results demonstrated that all birds appeared  normal, with all gastrointestinal histologic lesions and liver histologic lesions  identified within normal limits for broiler chickens in a production environment.  Phase 2 trial showed that the lowest amount of Berberine, 0.03 g/kg in-feed,  resulted in tissue residues below the lower limit of detection (<2 ng/g), and the  highest amount of Berberine, 0.3 g/kg in-feed, yielded detectable values, although  the significance of these results is still not clear. Conclusions: In conclusion, the present study suggests that the five tested  phytogenic compounds are safe for use in starter, grower and finisher feeds for  broiler chickens. Further exposure and risk assessment calculations regarding  appropriate residue levels are necessary to evaluate the use of Berberine as a  feed ingredient for poultry.

Target Animal Safety and Residual Study for Berberine and other Phytogenic Compounds in Broiler Chickens