English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

There is no doubt that determination of the absolute configuration of isolated natural products or synthesized compounds remains one of the most important tasks in all fields of chemistry, biochemistry, structural biology and medicinal chemistry. This is unquestionably due to the fact that biological activity is closely related to the stereostructure of bioactive compounds. Therefore, access to methods allowing simple and primarily unequivocal determination of their absolute configuration (AC) and/or conformation is of particular significance. Such a role is at present fulfilled by chiroptical techniques. In the last two decades chiroptical spectroscopy has been one of the most rapidly developing areas of chiral analysis due to the availability of modern, highly specialized and dedicated to particular chiroptical techniques commercial instruments. Recent progress in ab initio simulations of chiroptical properties has also significantly contributed to the increase of the use of chiroptical spectroscopy as a stereochemistry probe [1]. It is generally accepted that combined experimental and theoretical analysis opens much broader application opportunities for chiroptical spectroscopy by giving theoretical basis to experimental results [1-4]. Moreover, utilization of multiple (at least two) chiroptical techniques increases the confidence level of the stereochemical assignment and is nowadays considered by many authors to be the best practice [1-5].

Complementarity of Electronic and Vibrational Circular Dichroism Spectroscopy in Structure Determination of Vic-Amino Alcohols