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Inflammatory pseudotumor (IPT)-like follicular dendritic cell tumor (FDCT) has been recently designated1 and characterized by proliferation of Epstein-Barr virus (EBV)-positive follicular dendritic cell (FDC) and commonly occurs in the liver and spleen.2-9 Histologically, it is characterized by spindle cell proliferation admixed with abundant inflammatory cells, mainly lymphocytes and plasma cells. At present, the preferred term 'inflammatory myofibroblastic tumor' is used, because it has been shown that the proliferating spindle cells show a myofibroblastic phenotype in many cases.1 About 20 cases have been reported,2,9 although only one case has been reported in Korea.9 We present here a rare case of IPT-like FDCT of the spleen with extensive histiocytic granulomas and necrosis, including a brief literature review.

the korean journal of pathology/the korean journal of pathology

Inflammatory Pseudotumor-like Follicular Dendritic Cell Tumor of the Spleen with Extensive Histiocytic Granulomas and Necrosis: A Case Report and Literature Review