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A significant global impact from dementia: According to the World Health Organization (Dua et al., 2017), the current numbers for the prevalence and treatment costs for dementia worldwide are staggering. Almost 50 million individuals suffer from dementia. Dementia is now considered to be the 7 leading cause of death. Currently, at least five percent of the world’s elderly population, equal to approximately 47 million individuals, have dementia. Moreover, at least sixty percent reside in low and middle income countries. Almost seventy-five percent of these new cases are to occur in these countries. The number of new cases each year throughout the globe is increasing at approximately 10 million per year. By the year 2030, 82 million people are expected to have dementia and by the year 2050, 152 million are expected to have the disease. In regards to costs, it is estimated that greater than $800 billion United States dollars are spent to care for individuals with dementia on an annual basis. Such costs are greater than one percent of the global gross domestic product. By the year 2030, medical and social services could be overwhelmed with costs rising in the US alone to 2 trillion United States dollars annually. Furthermore, individual families encounter significant financial costs that involve social and adult living care as well as informal and companion care. In high-income countries, these costs for social care and informal care are almost shared in a fifty percent to fifty percent fashion but in low income countries, sufficient resources may only be available to provide fifteen percent of the expected costs. In conjunction with the expected growing care needs to assist those with new onset as well as progressive dementia, the World Health Organization estimates the need for close to sixty million new health and social care workers. Implementing the need for these healthcare workers can sometimes be difficult since the onset and progression of dementia in individuals is not always well recognized. Dementia and cognitive loss is considered to be under diagnosed throughout the world. Once diagnosis is correctly performed, it can be in the late stages of the disease and care can become disjointed over time. Furthermore, the desires of those with dementia may not be respected or poorly understood which can further complicate care for affected individuals.

neural regeneration research/neural regeneration research

Impacting dementia and cognitive loss with innovative strategies: mechanistic target of rapamycin, clock genes, circular non-coding ribonucleic acids, and Rho/Rock