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Dichloromethane and methanol extracts o f 48 lichens collected from six areas i n Sri Lanka were subjected to mosquitolarvicidal assay against t h e second instar larvae o fAedes aegypti and antifungal assay against Cladosporium cladosporioides. T h e following extracts showed significant mosquitolarvicidal activity. CH,Cl,: Cladonia coniocraea, Everniastrum sp., Parmelina tiliaceae, Parmotrema chinense, Parmo t rema t i n c t o r u m , R i m e l i a r e t i cu la ta , D i r inar ia applanta , Heterodermia leucomelos, Roccella montagnei, Stereocaulon sp., Ocellularia sp., two species o f Myriotrema, and Usnea sp . MeOH: Hypogymnia sp. , H . leucomelos, Lepraria atrotomentosa. T h e CH,Cl,extracts o f C. coniocraea, Hypogymnia sp., Lecanora sp., Parmeliella sp., Everniastrum sp., Heterodermia diademata, H. leucomelos, R . montagnei, and Usnea sp., exhibited potent antifungal activity. Lichens have not been subjected to comprehensive bioassays unlike the flowering plants. Recently, however, there have been some reports of screening of lichen metabolites, particularly for antibiotic a ~ t i v i t y . ~ , ~ , ~ ) ~ Large pharmaceutical companies have initiated screening programs for application of these metabolites and their derivatives in medicine and crop pro tec t i~n .~ In this investigation we report the bioactivities of some lichens of Sri Lanka, against the second instar larvae of Aedes aegypti and the fungus Cladosporium cladosporioides. METHODOLOGY

Effect of Some Lichen Extracts from Sri Lanka on Larvae Ofaedes Aegypti and the Fungus Cladosporium Cladosporioides