English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Metal-free decarboxylative coupling reaction of phenylpropiolic acid, paraformaldehyde, and morpholine was monitored by NMR spectroscopy ( 1 H, 13 C NMR, NOE, DOSY, COSY HMBC, and HSQC). Hemiaminal and bisaminal were obtained from the reaction with paraformaldehyde and morpholine. The resulting hemiaminal was more reactive than the corresponding bisaminal in the reaction with phenylpropiolic acid. The decarboxylative coupling with hemiaminal and phenylpropiolic acid may be the major pathway, producing the desired phenylpropargylamine.

Mechanistic studies on the metal-free decarboxylative coupling reaction for synthesis of propargylamines by NMR