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Potential precursors have been prepared for intramolecular 1,3-dipolar cycloaddition to form a pyrrolo(3,4-b)isoxazole. The cycloaddition has not to date been accomplished, however an unexpected retro-Claisen reaction is reported.

Explorations of an intramolecular route to pyrrolo[3,4-b]isoxazoles: an unexpected retro-Claisen reaction