English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Treatment of 2-cyano-N-(2-pyridyl)acetamide (1) with hydrazonoyl chlorides 2a-e afforded aminopyrazoles 4a-e which on treatment with sodium nitrite in acetic acid furnished the pyrazolo[3,4-d]-1,2,3-triazin-4-one derivatives 8a-e. Reaction of aminopyrazoles 4c-e with triethylorthoformate in glacial acetic acid afforded pyrazolo[3,4-d]pyrimidin-4-one derivatives 10a-c. Compound 1 reacted with DMF-DMA in refluxing xylene affording a mixture of 3-(N,Ndimethylamino)propenenitrile 11 and N,1-di(pyridin-2-yl)pyridine-3-carboxamide 15 derivatives. When compound 11 was treated with hydrazine, phenylhydrazine or with 5-amino3-phenyl-1H-pyrazole 16 in refluxing ethanol, the novel aminopyrazoles 13a,b and pyrazolo[1,5a]pyrimidine 18 derivatives were obtained.

Facile route to novel 2-pyridone, pyrazolo[3,4-d]-1,2,3-triazine, and pyrazolo[3,4-d]- and [1,5-a]-pyrimidine derivatives