English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The one-pot reaction of phenylacetaldehyde with a primary amine followed by tosyl azide yields the corresponding benzamidine 1 along with the N-monosubstituted-N-tosylformamidine 2. The participation of α-amino acid esters as reactants permitted the base-promoted intramolecular condensations of benzamidines 1d, 1e, 1f and 1i to give the corresponding 1,2-dihydropyrol-3ones 6a-6d, respectively. The combination of phenylacetaldehyde, a pair of heterocyclic secondary amines, and 4-nitrophenyl azide in turn led to the two dihydrotriazole derivatives, 4b and 4c. Loss of nitrogen from 4 in refluxing toluene afforded trisubstituted benzamidines 5b and 5c, that also undergo base-promoted intramolecular condensation, forming 1,2-dihydropyrrol-3ones 7a and 7b in turn.

Synthesis of phenylacetaldehyde amidines and their intramolecular cyclization