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Quinazolinediones derivatives are a new family of diphenyl ether herbicides. Twenty four 1,3substituted quinazolinediones derivatives were designed and synthesized. Their structures were confirmed by H NMR and elemental analysis. The preliminary bioassay results show that most of these compounds have herbicidal activity in post-emergence treatment. The compounds 3c, 3d, 3e, 3f showed 90-100% herbicidal efficacy at 200 gha against dicotyledonous weeds such as Abutilon theophrasti.

Synthesis and herbicidal activity of 1,3-substituted quinazolinedione derivatives