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In  Turkey,  lenalidomide  plus  dexamethasone  (RD)  has  been  used  to  treat  relapsed/refractory  multiple  myeloma   (RRMM)  since  2010.  This  retrospective,  single-center  study  evaluated  the  efficacy  and  tolerability  of  RD  in  patients  with  RRMM   between October 2010 and June 2016.