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The predictive and prognostic value of KRAS mutation and its type of mutations in non-small cell lung cancer (NSCLC) are controversial. This clinical study was designed to investigate the predictive value of KRAS mutations and its mutation types to pemetrexed and gemcitabine based treatment.

KRAS G12C mutation as a poor prognostic marker of pemetrexed treatment in non-small cell lung cancer