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With the current emergent situation of Coronavirus disease-19 (COVID-19) pandemic all over the world, the need for ventilators increases every day. About 1-3% of COVID-19 patients can develop acute respiratory distress syndrome (ARDS) that ranges from mild to severe [1]. So, the shortage of mechanical ventilators is expected to be a critical problem in many countries. Non-invasive ventilation (NIV) may help in the Management of COVID-19 patients. It does not replace invasive mechanical ventilation but can provide a bridge to it [2]. In China, more than 50% of treated patients required NIV or High Flow Nasal Cannula [3]. However, the World Health Organization (WHO) reported NIV as a high-risk aerosolgenerating procedure, increasing the risk of infection transmission, especially to healthcare providers [4].

The Role of Non-Invasive Ventilation (NIV) in the Era of COVID-19 Pandemic