Open AccessIntestinal damage mediated by Kupffer cells in rats with endotoxemia
Author(s) -
Jianping Gong
Publication year - 2002
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v8.i5.923
Subject(s) - ileum , proinflammatory cytokine , kupffer cell , chemistry , tumor necrosis factor alpha , medicine , intestinal mucosa , necrosis , endocrinology , in vivo , bile duct , pathology , inflammation , biology , microbiology and biotechnology
To determine the in vivo effects of phagocytic blockade of Kupffer cell (KC) on the release of proinflammatory cytokines in small intestinal lesion and on the integrity of intestinal tract by using gadolinium chloride (GdCl(3)) during early endotoxemia.