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To compare the effect of University of Wisconsin (UW) solution with or without metformin, an AMP-activated protein kinase (AMPK) activator, for preserving standard and marginal liver grafts of young and aged rats ex vivo by hypothermic machine perfusion (HMP).

world journal of gastroenterology

Hypothermic machine perfusion with metformin-University of Wisconsin solution for <i>ex viv</i><i>o</i> preservation of standard and marginal liver grafts in a rat model

Hypothermic machine perfusion with metformin-University of Wisconsin solution for ex vivo preservation of standard and marginal liver grafts in a rat model