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The Corona Virus Disease 2019, caused by novel Coronavirus SARS-CoV-2 is an acute respiratory and systemic illness, and is declared as a global pandemic by WHO on the 11 th of March 2020.Only 2.2% to 1.7% of pediatric COVID-19 cases have been reported from USA and China respectively. The hematological parameter alteration in the pediatric COVID-19 cases needs to be addressed in the Indian population. Aim: To assess the alteration of the baseline hematology parameters in the paediatric COVID-19 cases and to compare the values with the adult COVID-19 cases for any statistically significant difference. Methods: A single Centre retrospective study of 11 COVID-19 asymptomatic pediatric patients and asymptomatic gender-matched adult cases admitted to SSPH&PGTI NOIDA from March to April, were enrolled for the study. The demographic date, baseline hematological findings of both groups were recorded and analyzed statistically. Results: Demographic characterization shows a mean age of 8.7 years in the pediatric population. Baseline CBC findings of all the pediatric cases show mild anemia, normal leucocyte, normal absolute lymphocyte count, and neutrophilia.Majority of the pediatric cases have NLR value below the cut-off point of 3.13.PLR was slightly higher in pediatric cases. Comparison between two groups shows statistically significant differences for the hemoglobin and platelet value only. Conclusion: The comparative analysis of baseline hematologic parameters did not show any significant derangement of the CBC parameters in pediatric cases. Significance in the difference of Hemoglobin level and platelet count is observed in comparison to the adult cases.

saudi journal of pathology and microbiology

Novel Insights into the Hematological Parameter Abnormalities in Pediatric COVID-19 Cases: Observation from A Preliminary Study of 11 Pediatric COVID-19 Cases in A Tertiary Care Center of North India