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HAV is transmitted through faeco-oral either by direct contact or by consumption of contaminated water/food. The virus multiplies in the intestinal epithelium and reaches the liver by hematogenous spread. Globally, the HAV prevalence in the population is directly related to the improved socio economic and sanitation levels worldwide. Hence, less developed countries such as Africa, Asia and Central and South America with very poor sanitary and hygienic conditions, HAV 3 infections is highly endemic .

A STUDY ON THE PREVALENCE AND SEASONAL VARIATION OF HEPATITIS A IN PATIENTS ATTENDING JNIMS HOSPITAL