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Mucormycosis is a rare invasive fungal infection of the nasal cavity and paranasal sinus, which often has an acute fulminant course. Mainstays of therapy are the reversal of the source of immunocompromise, surgical debridement of nonviable tissue, and systemic antifungals. Indolent mucormycosis is a rare entity that affects both immunosuppressed and immunocompetent individuals. Additionally, its clinical evolution is nonspecific, and there is no standardized treatment for this condition. Some reports suggest that immunocompetent patients should only be treated surgically. However, indolent mucormycosis in the complete remission state of chronic lymphocytic leukemia has not been reported. Herein we report a case of indolent mucormycosis of the sphenoid sinus in a patient with chronic lymphocytic leukemia in complete remission state with a review of the related literature. (J Clinical Otolaryngol 2020;31:78-82)

A Case of Indolent Mucormycosis of the Sphenoid Sinus in a Patient with Chronic Lymphocytic Leukemia in Complete Remission State