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The aim of this study is to identify CYP2C19*2 single nucleotide polymorphisms in patients with gastritis at TraVinh General Hospital. A cross-sectional study was conducted in 280 endoscopic gastric biopsy samples of patients with gastritis at TraVinh General Hospital. CYP2C19*2 genotypes were determined by realKhoa Y Dược, Trường Đại học Trà Vinh Đại học Y Dược Thành phố Hồ Chí Minh Ngày nhận bài: 12/06/2018; Ngày nhận kết quả bình duyệt: 19/09/2018; Ngày chấp nhận đăng: 26/03/2019 Email: ngoanhduy@tvu.edu.vn School of Medicine and Pharmacy, Tra Vinh University University of Medicine and Pharmacy Ho Chi Minh city Received date: 12 June 2018 ; Revised date: 19 September 2018; Accepted date: 26 March 2018 time PCR method using TaqMan probes. Data were stored and analyzed by IBM SPSS Statistic (version 20.0; Armonk, New York, USA) and Excel 2010. The prevallelece of GG, AG and AA genotypes were 51.8, 39.6 and 8.6% correspondingly. The ratio of allele G and A were 0.716 and 0.284 respectively. The correlation of CYP2C19*2 polymorphisms with age (p=0.891), gender (p=0.652) was not significantly distinguished

khoa học

APPLICATION OF THE REAL – TIME PCR FOR THE DETECTION OF CYP2C19*2 SINGLE NUCLEOTIDE POLYMORPHISM IN PATIENS WITH GASTRITIS AT TRA VINH GENERAL HOSPITAL