English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Background : Biofilm formation in  S. aureus  may reduce the rate of penetration of antibiotics, thereby complicating treatment of infections caused by these bacteria. The aim of this study was to correlate biofilm-forming potentials, antimicrobial resistance, and genes in  S. aureus  isolates.  Methods : A total of 64 milk samples were analysed, and 77  S. aureus  were isolated.  Results : Seventy (90.9%) isolates were biofilm producers. The  ica  biofilm-forming genes were detected among 75.3% of the isolates, with  ica A being the most prevalent (49, 63.6%). The  ica B gene was significantly ( P  = 0.027) higher in isolates with strong biofilm formation potentials. High resistance (60%–90%) of the isolates was observed against ceftriaxone, vancomycin, and penicillin, and 25 (32.5%) of  S. aureus  showed multidrug resistance (MDR) to at least three antibiotics. Five resistance genes, namely  blaZ  (29, 37.7%),  vanC  (29, 37.7%),  tetK  (24, 31.2%), tetL (21, 27.3%), and  msrA/B  (16, 20.8%) were detected. Most MDR phenotypes possessed at least one resistance gene alongside the biofilm genes. However, no distinct pattern was identified among the resistance and biofilm phenotypes.  Conclusions : The high frequency of potentially pathogenic MDR  S. aureus  in milk samples intended for human consumption, demonstrates the public health relevance of this pathogen in the region.

antibiotics

Genotypic and Phenotypic Evaluation of Biofilm Production and Antimicrobial Resistance in Staphylococcus aureus Isolated from Milk, North West Province, South Africa