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Reregulation of biochemical profile of host as a result of host cells-pathogen interaction may involve in pathogenesis of toxoplasmosis disease. The biochemical parameters in the placenta of Toxoplasma-infected pregnant women and noninfected pregnant women (control group) were investigated The criteria taken into consideration are: Superoxide dismutase (SOD) , Peroxidase (Px) , GlutathioneStransferase (GST) , Lactate dehydrogenase (LDH) , Aryl esterase (AE) , Acetylcholine esterase (AchE) , Vitamin A,C and E As well as placental electrolytes including: Sodium (Na) , Potassium (K) , Chloride (Cl) , Calcium (Ca) , Selenium (Se) , Cupper (Cu) , Zinc (Zn) , Iron (Fe) , Magnesium (Mg) and Manganese (Mn). The results showed: a non-significant increase in the activity of SOD, GST, LDH and AchE during 6-9 months, and activity of AE during 1-3 months, were determined whereas the activity of Px was decreased in all periods of pregnancyA nonsignificant increase in the level of vitamin E and non-significant decrease in levels of vitamin A and C during pregnancy periods in placentae of infected pregnant Were observed. . A significant increase (p≤0.01) in levels of Na and K during 1-3 months and Ca during 3-6 months, whereas the level of Cl decreased during pregnancy periods. A significant increase (p≤0.01) in levels of Seand Mg during 6-9 months and a nonsignificant increase in level of Cu during 1-3 months and 6-9 months, whereas the level of Zn, Fe and Mn significantly decreased in all periods of Pregnancy in placenta infected women.

Effect of Some Biochemical Parameters as Antioxidants in Placenta of infected Pregnant Weman with Toxoplasmosis